10. Sun Bay on Vieques Island
9. Flamenco Beach on Culebra Island
8. Rio Camuy Caves
7. Panoramic Route (Ruta Panoramica)
6. Ponce
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- Plaza Las Delicias
- Old Ponce Fire Station
- City Hall
- Catedral Nuestra Señora de la Guadalupe
- Ponce Museum of Art
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5. Barranquitas and San Cristobal Canyon
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- Plaza Pública Mons. Miguel Ángel Mendoza
- Parroquia San Antonio de Padua
- Centro Cultural de Barranquitas
- Castillo El Cortijo
- Paseo Lineal and Tourism Mirador de Barranquitas
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4. Arecibo
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- Arecibo Observatory
- Arecibo Lighthouse and Historical Park, plus Poza del Obispo (cove with swimming beach and tide pools)
- Catedral de San Felipe Apóstle and Plaza
- Cueva del Indio (Taino petroglyphs)
- Cueva Ventana (best silhouette photos)
- Rio La Planta (two waterfalls)
- Bosque Cambalache Park (Cambalache Forest Reserve)
- Camuy River Cave Park (home to thousands of bats)
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3. Bioluminescence
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- Laguna Grande – Town of Fajardo (east coast)
- La Parguera – Town of Lajas (southwest coast)
- Mosquito Bay – Isla de Vieques
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2. El Yunque National Forest
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- La Coca Waterfall
- Juan Diego Falls
- Cascada La Mina (La Mina Falls)
- Big Tree Trail
- Caimitillo Trail
- Torre Yokahu (observation tower)
- El Yunque Peak Tower (observation tower)
- El Toro Peak
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1. San Juan
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- San Juan National Historic Site
- La Fortaleza
- Viejo San Juan (Old San Juan)
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