North to south – from Indiana-Michigan state line south:
Niles, Michigan
Michigan-Indiana state line
Roseland
Notre Dame
South Bend – crossroad of Lincoln Highway Historic Byway and historic Dixie Highway, as well as Michigan Road Historic Byway and historic Detroit-Lincoln-Denver Highway
Lakeville
Plymouth
Rochester
Logansport
Indianapolis
Martinsville
Bloomington
Bedford
Paoli
New Albany (Ohio River area)
Jeffersonville (Ohio River area)
Falls of the Ohio State Park (Clarksville, Indiana) (Ohio River area)
Indiana-Kentucky state line (Ohio River)
Louisville, Kentucky